INTERPOSITUM

\ˌɪntəpˈɒsa͡ɪtəm], \ˌɪntəpˈɒsa‍ɪtəm], \ˌɪ_n_t_ə_p_ˈɒ_s_aɪ_t_ə_m]\

Definitions of INTERPOSITUM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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