LILLY 99638

\lˈɪli nˈa͡ɪntinˈa͡ɪn θˈa͡ʊzənd sˈɪkshˈʌndɹədən θˈɜːtiˈe͡ɪt], \lˈɪli nˈa‍ɪntinˈa‍ɪn θˈa‍ʊzənd sˈɪkshˈʌndɹədən θˈɜːtiˈe‍ɪt], \l_ˈɪ_l_i n_ˈaɪ_n_t_i_n_ˈaɪ_n θ_ˈaʊ_z_ə_n_d_ s_ˈɪ_k_s_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i__ˈeɪ_t]\

Definitions of LILLY 99638

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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