MARSDEN'S PASTE

\mˈɑːsdənz pˈe͡ɪst], \mˈɑːsdənz pˈe‍ɪst], \m_ˈɑː_s_d_ə_n_z p_ˈeɪ_s_t]\

Definitions of MARSDEN'S PASTE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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