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Definition of nadir:

That point of the heavens, or lower hemisphere, directly opposite the zenith; the inferior pole of the horizon; the point of the celestial sphere directly under the place where we stand.
The lowest point; the time of greatest depression.

Synonyms:

breaking point, rock bottom, milestone, lowest point, zero, depth, peak, highlight, the moment of truth, the point of no return, turning point, watershed, low-water mark, crossroads, climax, bedrock, opposite.

bottom (part of speech: noun)
- depths,
- base,
- sole,
- foot,
- foundation,
- underneath,
- basement,
- bottom,
- underside

Usage examples:

The Buddha told him that this was not the right way to protect oneself: a man should regard his parents as the east, his teachers as the south, his wife and children as the west, his friends as the north, his servants as the nadir and monks and Brahmans as the zenith.

- "Hinduism and Buddhism, Vol I. (of 3) An Historical Sketch", Charles Eliot.
It is said that under the reign of Nadir- Shah and his successors, they had again to elect between the frightful alternative of conversion or death.

- "Les Parsis", D. Menant.
The case is again altered, and very unfortunately altered, in the next, the most popular and, as has been said, the most famous of the series- its zenith at once and its nadir- Literature and Dogma.

- "Matthew Arnold", George Saintsbury.