OOGENESES
\ˈuːd͡ʒənˌɛsiːz], \ˈuːdʒənˌɛsiːz], \ˈuː_dʒ_ə_n_ˌɛ_s_iː_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.