ORISON SWETT MARDEN

\ˈɒɹɪsən swˈɛt mˈɑːdən], \ˈɒɹɪsən swˈɛt mˈɑːdən], \ˈɒ_ɹ_ɪ_s_ə_n s_w_ˈɛ_t m_ˈɑː_d_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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