PLEGAPHONIA
\plˌɛɡɐfˈə͡ʊni͡ə], \plˌɛɡɐfˈəʊniə], \p_l_ˌɛ_ɡ_ɐ_f_ˈəʊ_n_iə]\
Definitions of PLEGAPHONIA
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.