RETROGRADED
\ɹˌɛtɹə͡ʊɡɹˈe͡ɪdɪd], \ɹˌɛtɹəʊɡɹˈeɪdɪd], \ɹ_ˌɛ_t_ɹ_əʊ_ɡ_ɹ_ˈeɪ_d_ɪ_d]\
Definitions of RETROGRADED
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.