ROLLER'S NUCLEUS
\ɹˈə͡ʊləz njˈuːklɪəs], \ɹˈəʊləz njˈuːklɪəs], \ɹ_ˈəʊ_l_ə_z n_j_ˈuː_k_l_ɪ__ə_s]\
Definitions of ROLLER'S NUCLEUS
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.