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\stˈɒkɛkst͡ʃˈe͡ɪnd͡ʒ], \stˈɒkɛkst‍ʃˈe‍ɪnd‍ʒ], \s_t_ˈɒ_k_ɛ_k_s_tʃ_ˈeɪ_n_dʒ]\
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1871 - The Cabinet Dictionary of the English Language

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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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