TOPHUS SYPHILITICUS

\tˈɒfəs sˌa͡ɪfɪlˈɪtɪkəs], \tˈɒfəs sˌa‍ɪfɪlˈɪtɪkəs], \t_ˈɒ_f_ə_s s_ˌaɪ_f_ɪ_l_ˈɪ_t_ɪ_k_ə_s]\

Definitions of TOPHUS SYPHILITICUS

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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