WOELFLER'S OPERATION'S SIGN

\wˈə͡ʊlfləz ˌɒpəɹˈe͡ɪʃənz sˈa͡ɪn], \wˈə‍ʊlfləz ˌɒpəɹˈe‍ɪʃənz sˈa‍ɪn], \w_ˈəʊ_l_f_l_ə_z ˌɒ_p_ə_ɹ_ˈeɪ_ʃ_ə_n_z s_ˈaɪ_n]\

Definitions of WOELFLER'S OPERATION'S SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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