DOLICHOCEPHALIA

\dˌɒlɪt͡ʃə͡ʊsfˈe͡ɪli͡ə], \dˌɒlɪt‍ʃə‍ʊsfˈe‍ɪli‍ə], \d_ˌɒ_l_ɪ_tʃ_əʊ_s_f_ˈeɪ_l_iə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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