KATAGENESIS

\kˌate͡ɪd͡ʒˈɛnɪsˌɪs], \kˌate‍ɪd‍ʒˈɛnɪsˌɪs], \k_ˌa_t_eɪ_dʒ_ˈɛ_n_ɪ_s_ˌɪ_s]\
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1920 - A dictionary of scientific terms (6th edition)
By J.H. Kenneth

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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