MEDIATE CONTACT

\mˈiːdɪˌe͡ɪt kˈɒntakt], \mˈiːdɪˌe‍ɪt kˈɒntakt], \m_ˈiː_d_ɪ__ˌeɪ_t k_ˈɒ_n_t_a_k_t]\

Definitions of MEDIATE CONTACT

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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