BENEDICT SYNDROME
\bˈɛnɪdˌɪkt sˈɪndɹə͡ʊm], \bˈɛnɪdˌɪkt sˈɪndɹəʊm], \b_ˈɛ_n_ɪ_d_ˌɪ_k_t s_ˈɪ_n_d_ɹ_əʊ_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.