CHARCOTS JOINT
\t͡ʃˈɑːkɒts d͡ʒˈɔ͡ɪnt], \tʃˈɑːkɒts dʒˈɔɪnt], \tʃ_ˈɑː_k_ɒ_t_s dʒ_ˈɔɪ_n_t]\
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Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.