FABIEN PILLET
\fˈabi͡ən pˈɪlɪt], \fˈabiən pˈɪlɪt], \f_ˈa_b_iə_n p_ˈɪ_l_ɪ_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.