II3NEUACLACCER
\ˌa͡ɪˈa͡ɪ θɹˈiː njˈuː ˌe͡ɪsˈiː lˈak sˈɜː], \ˌaɪˈaɪ θɹˈiː njˈuː ˌeɪsˈiː lˈak sˈɜː], \ˌaɪ__ˈaɪ θ_ɹ_ˈiː n_j_ˈuː ˌeɪ_s_ˈiː l_ˈa_k s_ˈɜː]\
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A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G (M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G (M2) ganglioside from G (M3) ganglioside and is the cause of an anabolic sphingolipidosis.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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