IRRITATIVE FEVER

\ˈɪɹɪtˌe͡ɪtɪv fˈiːvə], \ˈɪɹɪtˌe‍ɪtɪv fˈiːvə], \ˈɪ_ɹ_ɪ_t_ˌeɪ_t_ɪ_v f_ˈiː_v_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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