ISOASPARTIC ACID
\ˌa͡ɪsə͡ʊspˈɑːtɪk ˈasɪd], \ˌaɪsəʊspˈɑːtɪk ˈasɪd], \ˌaɪ_s_əʊ_s_p_ˈɑː_t_ɪ_k ˈa_s_ɪ_d]\
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An ASPARTIC ACID residue in polypeptide chains that is linked at the beta-carboxyl group instead of at the normal, alpha-carboxyl group, polypeptide linkage. It is a result of the spontaneous decomposition of aspartic acid or ASPARAGINE residues.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.