JULIAN HAWTHORNE

\d͡ʒˈuːli͡ən hˈɔːθɔːn], \d‍ʒˈuːli‍ən hˈɔːθɔːn], \dʒ_ˈuː_l_iə_n h_ˈɔː_θ_ɔː_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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