NEW AMSTERDAM

\njˈuː ˈamstədˌam], \njˈuː ˈamstədˌam], \n_j_ˈuː ˈa_m_s_t_ə_d_ˌa_m]\
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2006 - WordNet 3.0
By Princeton University
 
1894 - Dictionary of United States history
By John Franklin Jameson

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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