PAK65
\pˈak sˈɪkstifˈa͡ɪv], \pˈak sˈɪkstifˈaɪv], \p_ˈa_k s_ˈɪ_k_s_t_i_f_ˈaɪ_v]\
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A protein serine/threonine kinase which is involved in cell transformation by polyoma virus and is connected to the expression of IGF2. The immunosuppressant rapamycin inhibits the activation of the kinase, leading to reduced translation of certain mRNAs and a decrease in protein synthesis. EC 2.7.10.-.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.