POSTHEPARIN LIPASE
\pˈə͡ʊsthɪpəɹˌɪn lˈɪpe͡ɪs], \pˈəʊsthɪpəɹˌɪn lˈɪpeɪs], \p_ˈəʊ_s_t_h_ɪ_p_ə_ɹ_ˌɪ_n l_ˈɪ_p_eɪ_s]\
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An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
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