PYRUVATE METABOLISM, INBORN ERRORS
\pˈa͡ɪɹuːvˌe͡ɪt mətˈabəlˌɪzəm], \pˈaɪɹuːvˌeɪt mətˈabəlˌɪzəm], \p_ˈaɪ_ɹ_uː_v_ˌeɪ_t m_ə_t_ˈa_b_ə_l_ˌɪ_z_ə_m]\
Sort: Oldest first
-
Hereditary disorders of pyruvate metabolism. They are difficult to diagnose and describe because pyruvate is a key intermediate in glycolysis, gluconeogenesis, and the tricarboxylic acid cycle. Some inherited metabolic disorders may alter pyruvate metabolism indirectly. Disorders in pyruvate metabolism appear to lead to deficiencies in neurotransmitter synthesis and, consequently, to nervous system disorders.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.