SURROGATE ENDPOINTS
\sˈʌɹəɡˌe͡ɪt ˈɛndpɔ͡ɪnts], \sˈʌɹəɡˌeɪt ˈɛndpɔɪnts], \s_ˈʌ_ɹ_ə_ɡ_ˌeɪ_t ˈɛ_n_d_p_ɔɪ_n_t_s]\
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Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.