ABL PROTO ONCOGENE PROTEINS
\ˈabə͡l pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈə͡ʊtiːnz], \ˈabəl pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈəʊtiːnz], \ˈa_b_əl p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈəʊ_t_iː_n_z]\
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Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
By DataStellar Co., Ltd
Nearby Words
- abl genes
- abl oncogene
- abl oncogene proteins
- abl oncogenes
- abl proto oncogene products
- abl Proto Oncogene Proteins
- ablactate
- ablactation
- ablaqueate
- ablaqueation
- ablastemic