ARCHAEAL TOPOISOMERASES II
\ɑːkˈi͡əl tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪzɪz ɹˌə͡ʊmən tˈuː], \ɑːkˈiəl tˈɒpɔɪsˌəʊmɹeɪzɪz ɹˌəʊmən tˈuː], \ɑː_k_ˈiə_l t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z_ɪ_z ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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Archaeal enzymes of the DNA TOPOISOMERASES, TYPE II class that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex.
By DataStellar Co., Ltd
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