COMPLICATED FRACTURE
\kˈɒmplɪkˌe͡ɪtɪd fɹˈakt͡ʃə], \kˈɒmplɪkˌeɪtɪd fɹˈaktʃə], \k_ˈɒ_m_p_l_ɪ_k_ˌeɪ_t_ɪ_d f_ɹ_ˈa_k_tʃ_ə]\
Definitions of COMPLICATED FRACTURE
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By Willam Alexander Newman Dorland
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.