DIABETIC ACIDOSES
\dˌa͡ɪəbˈɛtɪk ɐsˈɪdə͡ʊzɪz], \dˌaɪəbˈɛtɪk ɐsˈɪdəʊzɪz], \d_ˌaɪ_ə_b_ˈɛ_t_ɪ_k ɐ_s_ˈɪ_d_əʊ_z_ɪ_z]\
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Complication of diabetes resulting from severe insulin deficiency coupled with an absolute or relative increase in glucagon concentration. The metabolic acidosis is caused by the breakdown of adipose stores and resulting increased levels of free fatty acids. Glucagon accelerates the oxidation of the free fatty acids producing excess ketone bodies (ketosis).
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.