GABA(A) RECEPTOR
\ɡˈɑːbə ɐ ɹɪsˈɛptə], \ɡˈɑːbə ɐ ɹɪsˈɛptə], \ɡ_ˈɑː_b_ə__ ɐ__ ɹ_ɪ_s_ˈɛ_p_t_ə]\
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Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and control an integral membrane chloride channel. GABA-A receptors are the most prevalent inhibitory neurotransmitter receptors in the brain. Several isoforms have been cloned, and they belong to a superfamily which includes nicotinic receptors, glycine receptors, and 5HT-3 receptors. Most GABA-A receptors have separate modulatory sites sensitive to benzodiazepines and to barbiturates.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.