TRITAN DEFECT
\tɹˈa͡ɪtən dˈiːfɛkt], \tɹˈaɪtən dˈiːfɛkt], \t_ɹ_ˈaɪ_t_ə_n d_ˈiː_f_ɛ_k_t]\
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Defects of color vision are mainly hereditary traits but can be secondary to acquired or developmental abnormalities in the CONES (RETINA). Severity of hereditary defects of color vision depends on the degree of mutation of the OPSIN genes (on X CHROMOSOME and CHROMOSOME 3, HUMAN) that code the photopigments for red, green and blue.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.