COAGULATIVE

\kə͡ʊˈaɡjʊlətˌɪv], \kə‍ʊˈaɡjʊlətˌɪv], \k_əʊ_ˈa_ɡ_j_ʊ_l_ə_t_ˌɪ_v]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
 
1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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