GAMMATA FERRAMENTA

\ɡamˈɑːtə fˌɛɹəmˈɛntə], \ɡamˈɑːtə fˌɛɹəmˈɛntə], \ɡ_a_m_ˈɑː_t_ə f_ˌɛ_ɹ_ə_m_ˈɛ_n_t_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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