GUANINE NUCLEOTIDE RELEASING FACTORS

\ɡwˈɑːna͡ɪn njˈuːklɪˌɒta͡ɪd ɹɪlˈiːsɪŋ fˈaktəz], \ɡwˈɑːna‍ɪn njˈuːklɪˌɒta‍ɪd ɹɪlˈiːsɪŋ fˈaktəz], \ɡ_w_ˈɑː_n_aɪ_n n_j_ˈuː_k_l_ɪ__ˌɒ_t_aɪ_d ɹ_ɪ_l_ˈiː_s_ɪ_ŋ f_ˈa_k_t_ə_z]\

Definitions of GUANINE NUCLEOTIDE RELEASING FACTORS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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