NOVOBIOCIN
\nəvˈə͡ʊbɪˌɒsɪn], \nəvˈəʊbɪˌɒsɪn], \n_ə_v_ˈəʊ_b_ɪ__ˌɒ_s_ɪ_n]\
Definitions of NOVOBIOCIN
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By Princeton University
By DataStellar Co., Ltd
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An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.