AMYGDALO HIPPOCAMPAL EPILEPSY
\ˈamɪɡdəlˌə͡ʊ hˈɪpəkˌampə͡l ˈɛpɪlˌɛpsi], \ˈamɪɡdəlˌəʊ hˈɪpəkˌampəl ˈɛpɪlˌɛpsi], \ˈa_m_ɪ_ɡ_d_ə_l_ˌəʊ h_ˈɪ_p_ə_k_ˌa_m_p_əl ˈɛ_p_ɪ_l_ˌɛ_p_s_i]\
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Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.