DOMENICO CIAMPOLI

\dˈə͡ʊmnɪkˌə͡ʊ sˈa͡ɪəmpˌɒli], \dˈə‍ʊmnɪkˌə‍ʊ sˈa‍ɪəmpˌɒli], \d_ˈəʊ_m_n_ɪ_k_ˌəʊ s_ˈaɪ_ə_m_p_ˌɒ_l_i]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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