PURIMETHOL
\pjˈʊɹa͡ɪmθˌɒl], \pjˈʊɹaɪmθˌɒl], \p_j_ˈʊ_ɹ_aɪ_m_θ_ˌɒ_l]\
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An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.