TRANSLATIONAL FRAMESHIFTING
\tɹanslˈe͡ɪʃənə͡l fɹˈe͡ɪmʃɪftɪŋ], \tɹanslˈeɪʃənəl fɹˈeɪmʃɪftɪŋ], \t_ɹ_a_n_s_l_ˈeɪ_ʃ_ə_n_əl f_ɹ_ˈeɪ_m_ʃ_ɪ_f_t_ɪ_ŋ]\
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A directed change in translational reading frame that allows the production of a single protein from two or more overlapping genes. The process is programmed by the nucleotide sequence of the mRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in viruses (especially retroviruses), retrotransposons, and bacterial insertion elements but also in some cellular genes.
By DataStellar Co., Ltd
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