VP 16213
\vˌiːpˈiː sˈɪkstiːn θˈa͡ʊzənd tˈuːhˈʌndɹədən θˈɜːtiːn], \vˌiːpˈiː sˈɪkstiːn θˈaʊzənd tˈuːhˈʌndɹədən θˈɜːtiːn], \v_ˌiː_p_ˈiː s_ˈɪ_k_s_t_iː_n θ_ˈaʊ_z_ə_n_d_ t_ˈuː_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_iː_n]\
Sort: Oldest first
-
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
By DataStellar Co., Ltd
Word of the day
basidiomycota
- comprises fungi bearing the spores on basidium: Gasteromycetes (puffballs); Tiliomycetes (comprising orders Ustilaginales (smuts) and Uredinales (rusts)); Hymenomycetes (mushrooms; toadstools; agarics; bracket fungi); in some classification systems considered a division of kingdom comprises fungi bearing spores on a basidium; includes Gasteromycetes (puffballs) Tiliomycetes comprising the orders Ustilaginales (smuts) and Uredinales (rusts) Hymenomycetes (mushrooms, toadstools, agarics bracket fungi).