ACLASTIC
\ɐklˈastɪk], \ɐklˈastɪk], \ɐ_k_l_ˈa_s_t_ɪ_k]\
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Transmitting rays of light without refracting them. [Gr.]
By Smith Ely Jelliffe
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.