ALLEGHANY PLUM
\ˈalɪɡəni plˈʌm], \ˈalɪɡəni plˈʌm], \ˈa_l_ɪ_ɡ_ə_n_i p_l_ˈʌ_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.