GANGRENOUS ERGOTISM
\ɡˈaŋɡɹənəs ˈɜːɡətˌɪzəm], \ɡˈaŋɡɹənəs ˈɜːɡətˌɪzəm], \ɡ_ˈa_ŋ_ɡ_ɹ_ə_n_ə_s ˈɜː_ɡ_ə_t_ˌɪ_z_ə_m]\
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Chronic e. characterized by gangrene of the extremities due to persistent constriction of the arteries, preceded by itching and cutaneous anesthesia.
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.