GLYOXALASE I
\ɡlˈa͡ɪəksˌale͡ɪs ˈa͡ɪ], \ɡlˈaɪəksˌaleɪs ˈaɪ], \ɡ_l_ˈaɪ_ə_k_s_ˌa_l_eɪ_s ˈaɪ]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.