LEWY BODY PARKINSON DISEASE
\lˈuːi bˈɒdi pˈɑːkɪnsən dɪzˈiːz], \lˈuːi bˈɒdi pˈɑːkɪnsən dɪzˈiːz], \l_ˈuː_i b_ˈɒ_d_i p_ˈɑː_k_ɪ_n_s_ə_n d_ɪ_z_ˈiː_z]\
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A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
By DataStellar Co., Ltd
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Nearby Words
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