CONVULSIVE GENERALIZED SEIZURE DISORDER
\kənvˈʌlsɪv d͡ʒˈɛnəɹə͡lˌa͡ɪzd sˈiːʒə dɪsˈɔːdə], \kənvˈʌlsɪv dʒˈɛnəɹəlˌaɪzd sˈiːʒə dɪsˈɔːdə], \k_ə_n_v_ˈʌ_l_s_ɪ_v dʒ_ˈɛ_n_ə_ɹ_əl_ˌaɪ_z_d s_ˈiː_ʒ_ə d_ɪ_s_ˈɔː_d_ə]\
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Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71 (4):405-14)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.