RARITAS DENTIUM

\ɹˈɑːɹɪtəz dˈɛnti͡əm], \ɹˈɑːɹɪtəz dˈɛnti‍əm], \ɹ_ˈɑː_ɹ_ɪ_t_ə_z d_ˈɛ_n_t_iə_m]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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