CLONIDINE HYDROCHLORIDE
\klˈɒnɪdˌiːn hˈa͡ɪdɹəklˌɔːɹa͡ɪd], \klˈɒnɪdˌiːn hˈaɪdɹəklˌɔːɹaɪd], \k_l_ˈɒ_n_ɪ_d_ˌiː_n h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_aɪ_d]\
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An alpha-2 adrenergic agonist that crosses the blood-brain barrier. Clonidine acts centrally by reducing sympathetic tone, resulting in a fall in diastolic and systolic blood pressure and a reduction in heart rate. It also acts peripherally, and this peripheral activity may be responsible for the transient increase in blood pressure seen during rapid intravenous administration. (From Martindale, the Extra Pharmacopoeia, 30th ed, p350)
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Platidiam
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